If this is what you're picturing, don't be concerned — this isn't what we do.

Although revolutionary and beneficial, we're much less invasive to your personal space.

Industry-leading Cryo-Compression

ManaEZ Ice Braces provide industry-leading cryo-compression in the comfort of your own home.

(knee, ankle, shoulder, back, & hip)
View ManaEZ Ice Braces

State-of-the-Art, Localized Cryo-Compression

NICE1 Cold Compression Therapy devices provide state-of-the-art, localized cryo-compression in the comfort of your own home.

(knee, shoulder, spine, hip, lumbar, foot/ankle, wrist/hand & elbow)

Why Cryo-Compression was
Prescribed After Surgery

"Using cyrotherapy as a treatment for surgical wounds reduces pain by reducing inflammation and swelling, which lets more oxygen flow to cells.  At the same time, it slows down the metabolism of a cell so that less oxygen is needed. It also makes the nerve endings less sensitive to the pain." (8)

"Study of 55 patients, randomly 27 patients received cyrotherapy, 28 patients received no cyrotherapy after surgical intervention.....patients reported 50% pain reduction on day 1, day 3 and day 14 following surgery in the cyrotherapy group (WOMAC scores)....pain medication was reduced by 10% in cyrotherapy group compared to no cryrotherapy group" (8)

"Cold compression therapy units are more effective in concentrating the cold to the surgical site via a molded wrap. Cold water is then circulated through the wrap, delivering cold to all sides of the joint.  Compression helps to reduce swelling post surgery" (9)

“Patients treated with cold compression had significantly greater range of motion on all post-operative days (compared to ice bags). There was a general trend of lower average pain scores among cold compression patients at all follow-up intervals, with statistical significance reached on the 6th post-operative day. The mean functional knee scores were significantly higher in patients treated with cold compression compared to controls after three months of follow-up." (2)

“Dynamic intermittent compression combined with cryotherapy decreases analgesic drug requirements after ACL reconstruction and improves the postoperative recovery of range of knee motion.” (12)“Both intermittent compression and continuous cryotherapy are more effective in reducing post-traumatic edema than cool pack therapy. Intermittent compression showed the most significant reduction.” (11)

Most Common Applications


  • Arthroscopic stabilization or repair
  • Capsulolabral reconstruction
  • Clavicle fracture stabilization
  • Fracture fixations
  • Pain management
  • Shoulder debridement
  • Shoulder replacement
  • SLAP tear
  • Sprains, strains & fractures

Foot & Ankle

  • Achilles tendon rupture or tear
  • Lateral ankle repair
  • Ankle arthroscopy (ankle replacement)
  • Ankle fusion
  • Pain management
  • Plantar fasciitis and bone spurs
  • Sesamoiditis
  • Debridement
  • Sprain, strains & fractures
  • Tendon surgery

Lumbar (Lower Back)

  • Lumbar herniated disc
  • Lumbar spinal stenosis
  • Microdiscectomy
  • Laminectomy
  • Lumbar fusion
  • Spondylolisthesis
  • Lumbar degenerative disc disease
  • Synovial cyst
  • Nerve blocks
  • Pain management
  • Sprains, strains & fractures


  • Hip replacement surgery
  • Hip resurfacing
  • Revision hip surgery
  • Hip joint surgery
  • Nerve blocks
  • Pain management
  • Sprains, strains & fractures
  • Hip arthroscopic surgery


  • Meniscectomy
  • Meniscus repair
  • Full knee replacement
  • Plica surgery
  • Lateral release
  • Meniscus transplant
  • Tendon repair
  • ACL reconstructive surgery
  • Unicompartmental knee replacement
  • Microfracture surgery


  • Wrist fusion
  • Sprains, strains & fractures
  • Carpal tunnel release
  • Tendon repair
  • Wrist arthroscopy
  • Nerve repair
  • Wrist replacement
  • Knuckle (MCP joint) replacement
  • Trapeziectomy
  • Trigger finger
  • Finger joint fusion
  • Closed reduction and fixation
  • Finger and thumb joint replacement
  • Debridement

NICE1's Innovative Therapy System

Also known as cold compression, NICE1 is a combination of cryotherapy and active compression, which is commonly used to treat pain and inflammation after acute injury or surgical procedures. Cold therapy reduces pain due to its numbing effect on the injured area. The less pain you are in, the quicker you can recover. The primary reason for using cryotherapy in acute injury management is to lower the temperature of the injured tissue, which reduces the tissue's metabolic rate and helps the tissue to survive the period following the injury. It is well documented that metabolic rate decreases through the application of cryotherapy (10). Active compression is often used in conjunction with cryotherapy for the care of acute injuries. To date, the primary reason for using compression is to increase external pressure on the tissue to prevent edema formation (swelling). This occurs by hindering fluid loss from the vessels in the injured area, making it more difficult for fluids to accumulate. Ice combined with compression is significantly colder (yet safer) than ice alone due to improved skin contact and increased tissue density caused by extended static compression (10). Tissue reaches its lowest temperature faster and the tissue remains cool, even after treatment ends. Studies have shown that the body activates the hunting reaction after only 10 minutes of cryotherapy, at temperatures less than 49 °F (9.5 °C). The hunting response is a cycle of alternating vasoconstriction (decreased blood flow) and vasodilation (increased blood flow) that increases the delivery of oxygen and nutrient rich blood to the tissue. Increased blood flow can slow cell death, limit tissue damage, and aid in the removal of cellular debris and waste products.
NICE1 programmable pneumatic compression

Supporting Evidence

1. The role of cold compression dressings in the postoperative treatment of total knee arthroplasty. Levy AS, Marmar E Clin Orthop Relat Res. 1993 Dec; (297):174-8
2. Combination of cold and compression after knee surgery. A prospective randomized study. Schröder D, Pässler HH Knee Surg Sports Traumatol Arthrosc. 1994; 2(3):158-65.
3. The effect of cold therapy on the postoperative course of total hip and knee arthroplasty patients. Scarcella JB, Cohn BT Am J Orthop (Belle Mead NJ). 1995 Nov; 24(11):847-52.
4. The use of cold compression dressings after total knee replacement: a randomized controlled trial. Webb JM, Williams D, Ivory JP, Day S, Williamson DM Orthopedics. 1998 Jan; 21(1):59-61
5. Continuous-flow cold therapy after total knee arthroplasty.
Morsi E J Arthroplasty. 2002 Sep; 17(6):718-22.
6. Postoperative cryotherapy after total knee arthroplasty: a prospective study of 86 patients. Kullenberg B, Ylipää S, Söderlund K, Resch S J Arthroplasty. 2006 Dec; 21(8):1175-9.
7. Fastest reduction of posttraumatic edema: continuous cryotherapy or intermittent impulse compression? Stöckle U, Hoffmann R, Schütz M, von Fournier C, Südkamp NP, Haas N Foot Ankle Int. 1997 Jul; 18(7):432-8.
8. https://www.reuters.com/article/us-major-surgery-ice-pain-idUSKBN0EM1UY20140611
9. University of Utah Healthcare, 2018 Jan 1
10. Kullenberg, Björn; Ylipää, Staffan; Söderlund, Kerstin; Resch, Sylvia (2006-12-01). "Postoperative Cryotherapy After Total Knee Arthroplasty: A Prospective Study of 86 Patients". The Journal of Arthroplasty. 21 (8): 1175–117
9. doi:10.1016/j.arth.2006.02.159. ISSN 0883-5403. PMID 17162178.
11. Fastest Reduction of Post-traumatic Edema: Continuous Cryotherapy or Intermittent Impulse Compression, Stockle U et al, Foot Ankle Int 1997; 18 (7): 432-438
12. Cryotherapy with dynamic intermittent compression for analgesia after anterior cruciate ligament reconstruction, J. Murgiera, X. Cassardb

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